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| Vaccine, the ultimate solution (???) |
Jennifer Haller, a woman from California, took the first coronavirus vaccine given experimentally. It was March 17 this year. The trial of Covid-19 vaccine has started.
The invention of this vaccine mRNA 1273-credit is jointly owned by the Modern Bio Company of the United States and the National Institutes of Health (NIH) of this country. The second dose of the vaccine was given to Jennifer on 16 April. The vaccine is thought to prevent the SARS-COV-2 virus, which causes Covid-19 disease.
On the other hand, last week the University of Oxford in England started testing another SARS-COV-2 experimental vaccine in the human body. Whenever it became known that the coronavirus was about to take the shape of a pandemic, the global competition for effective vaccines began. At the moment, experiments with more than 140 vaccines have begun.
Why do you need a vaccine?
An effective and safe vaccine is needed to get rid of the current lockdown situation fearlessly. The virus has spread rapidly worldwide. This virus (SARS-CoV-2) is so contagious that it threatens human civilization. An effective and safe vaccine will be the only infallible weapon to save from economic loss, human death and suffering. Only then can we return to normal life. The good news is that we've come a long way in developing vaccines.
Why the delay in making the vaccine?
Vaccine development is complex and time consuming. The vaccine must be proven to be effective and safe to use. Remember that this vaccine will be given to millions of healthy people. There is no room for error here. The past history of vaccines has warned us about this.
What are the chances of a vaccine?
The idea is that an effective and safe vaccine is just a matter of time. With the financial support of all the rich countries of the world, the world's leading scientists and renowned scientific organizations have been engaged in inventing a vaccine. Johnson & Johnson, America's leading biomedical company, have announced a bill of 1 billion budget to develop a vaccine to prevent corona. In addition, the World Health Organization, in collaboration with the European Union, has undertaken a vaccine development project.
From the history of vaccines discovered to prevent different diseases, it is possible to make vaccines in different ways. For example, measles have been vaccinated by attenuating live viruses. The polio vaccine has been used to kill the virus and use the entire virus. Cholera and tetanus have been vaccinated against toxins. And modern technology is trying to use an essential part of the germ's survival, such as a genetic material or an important protein, to help infect the virus (such as the spike protein in the case of SARS-CoV-2), increasing the chances of the vaccine being safe.
However, which method will be effective for any disease, it is subject to testing. The matter of time is there.
The two most likely vaccines that are currently being discussed are the mRNA-1273 and the Oxford Covid-19 vaccine (ChAdox1).
The mRNA-1273 vaccine is being developed jointly by Modern Bio Company and the US National Institutes of Health. The vaccine is being developed using scientifically advanced technology. The genetic material of the Covid-19 virus (SARS-CoV-2), which is essential for the survival of the virus, has been developed separately in this vaccine. Its work began in 2012 when infection with the Mars virus began. Mars virus and Covid-19 virus (SARS-CoV-2) are closely related, so the advantage is to quickly develop this vaccine for a Covid-19 disease based on previous work. As I said before, the test of it has started in the human body. The success of this vaccine will be known soon. Experimentally, this is the first time that the vaccine has been applied to this woman's body.
Oxford Covid-19 vaccine (ChAdox1)
Scientists at the prestigious Oxford University in England have come a long way with this vaccine. This vaccine has been created in fancy ways. The vaccine has been planned to use a proven approach to the pre-vaccine history. The common cold virus (a similar coronavirus) is derived from chimpanzees and is killed by chemicals. Then it is mixed with the protein of Covid-19 virus (Stork-Cov 2). This is a very old technique. The polio vaccine was developed in this way many decades ago.
Testing of this vaccine has also started. According to the latest news, this vaccine has been able to prevent coronavirus infection in monkeys. This is very good news. The idea is that the effectiveness of this vaccine on humans will be known within this year.
Talk about rubbing salt in my wounds – Ouch!!!
It may be that no effective vaccine has been found to prevent Covid-19 disease. Or effective, but safe for the use of nine hundred thousands of people.
The reason for thinking about this ominous thing is the past history of vaccines. Those who are students of vaccine history know very well that the vaccine for the Covid-19 disease has potential, but not certain. For example, we have not yet been able to develop a vaccine against the HIV virus. The effort has been going on for more than three decades. So far, no vaccine has been approved for SOS and Mars viruses, which are related to the Covid-19 virus.
How safe it is with the effectiveness of the vaccine is also very important. The reaction to the vaccine may be such that it exacerbates the symptoms of the disease. We call this response increased immunity. This may increase the chances of disease rather than resistance. As was the case with the dengue vaccine. In the last few years, the dengue vaccine has been given to about four million Filipino schoolchildren, of whom six hundred have died. Many more fell ill. That is why this vaccine was later withdrawn from the market.
So there is no end to the precautions for new vaccines. This is a situation where you are scared to see the clouds in the cowshed. This may not be the case with coronavirus. More likely to be safe.
This is why the Modern Bio Company's vaccine uses parts of the genetic material that are essential for the survival of the virus. In this case, the vaccine is more likely to be safe and less effective.
In Conclusion
The key to creating any vaccine is to test-correct-re-test and ultimately success or failure. In the words of Jennifer Haller, the first volunteer of the vaccine trial, 'I hope we can quickly get an effective and safe vaccine that will save people's lives and we will go back to our normal lives.' True to Jennifer Haller's words.
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